The RUGER® P345™ pistols are chambered for the .45 Auto (.45 ACP) cartridge. Do not attempt to load any other .45 caliber cartridges into the magazine or chamber of the pistol.

The Ruger P-Series pistols are compatible with all factory ammunition of the correct caliber loaded to U.S. Industry Standards, including high-velocity and hollow-point loads, loaded in brass, aluminum, or steel cartridge cases. No .45 Auto ammunition manufactured in accordance with NATO, U.S., SAAMI, or CIP standards is known to be beyond the design limits or known not to function in these pistols.

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